Abstract Treatment of bacterial infections is one of the major challenges of our time due to the evolved resistance mechanisms of pathogens against antibiotics.To circumvent this problem, it is necessary to understand the mode of action of the drug and the mechanism of resistance of the pathogen.One of the most potent antibiotic targets is peptidog
Due to the flight characteristics such as small size, low noise, and high efficiency, studies on flapping wing robots are being actively conducted.In particular, the flapping Coriander wing robot is in the spotlight in the field of search and reconnaissance.Most of the research focuses on the development of flapping wing robots rather than autonomo
Qualitative interviews in the Isle of Man uncovered local perceptions of a tourism industry in late stage decline.Social impacts of decline are pronounced including facilities loss, cultural changes and a heightening of perceived peripherality: which taken together undermine local identity.Tourists are welcomed as they help Hat Accessories to affir
Objective: Postoperative delirium (POD) is a frequent complication after surgery and its occurrence is associated with poor outcomes.The pathophysiology of this complication is not clear, but identification of risk factors is important for positive postoperative outcomes.The purpose of this study was to investigate the associations between the preo
M Sandals Metabolic reprogramming is a hallmark of cancer.Somatic mutations in genes involved in oncogenic signaling pathways, including KRAS and TP53, rewire the metabolic machinery in cancer cells.We here set out to determine, at the single cell level, metabolic signatures in human colon cancer cells engineered to express combinations of activati